Sertraline is used to treat depression, obsessive-compulsive disorder (bothersome thoughts that wont go away and the need to perform certain actions over and over), panic attacks (sudden, unexpected attacks of extreme fear and worry about these attacks), posttraumatic stress disorder (disturbing psychological symptoms that develop after a frightening experience), and social anxiety disorder (extreme fear of interacting with others or performing in front of others that interferes with normal life). It is also used to relieve the symptoms of premenstrual dysphoric disorder, including mood swings, irritability, bloating, and breast tenderness. Sertraline is in a class of medications called selective serotonin reuptake inhibitors (SSRIs). It works by increasing the amounts of serotonin, a natural substance in the brain that helps maintain mental balance.
How should this medicine
be used ?
Sertraline comes as a tablet and a concentrate (liquid) to take by mouth. It is usually taken once daily in the morning or evening. To treat premenstrual dysphoric disorder, sertraline is taken once a day, either every day of the month or on certain days of the month. To help you remember to take sertraline, take it around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sertraline exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Sertraline concentrate must be diluted before use. Immediately before taking it, use the provided dropper to remove the amount of concentrate your doctor has directed you to take. Mix the concentrate with 4 ounces (1/2 cup) of water, ginger ale, lemon or lime soda, lemonade, or orange juice. Do not mix the concentrate with any liquids other than the ones listed. Drink immediately. Your doctor may start you on a low dose of sertraline and gradually increase your dose, not more than once a week. It may take a few weeks or longer before you feel the full benefit of sertraline. Continue to take sertraline even if you feel well. Do not stop taking sertraline without talking to your doctor. Your doctor or pharmacist will give you the manufacturer’s patient information sheet when you begin treatment with sertraline. Read the information carefully and ask your doctor or pharmacist if you have any questions.
What special precautions
i should follow ?
Before taking sertraline, tell your doctor and pharmacist if you are allergic to sertraline or any other medications. Before taking sertraline liquid concentrate, tell your doctor if you are allergic to latex. do not take sertraline if you are taking monoamine oxidase (MAO) inhibitors, including phenelzine (Nardil) and tranylcypromine (Parnate), or have stopped taking them within the past two weeks, or if you are taking pimozide (Orap). do not take disulfiram (Antabuse) while taking sertraline concentrate. tell your doctor and pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention any of the following: anticoagulants (blood thinners) such as warfarin (Coumadin); antidepressants (mood elevators) such as amitriptyline (Elavil), amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Adapin, Sinequan), imipramine (Tofranil), nortriptyline (Aventyl, Pamelor), protriptyline (Vivactil), and trimipramine (Surmontil); aspirin and other nonsteroidal anti-inflammatory medications (NSAIDs) such as ibuprofen (Advil, Motrin) and naproxen (Aleve, Naprosyn); cimetidine (Tagamet); diazepam (Valium); digoxin (Lanoxin); lithium (Eskalith, Lithobid); medications for anxiety, mental illness, Parkinsons disease, and seizures; medications for irregular heartbeat such as flecainide (Tambocor) and propafenone (Rythmol); oral medications for diabetes such as tolbutamide (Orinase); sedatives; sleeping pills; sumatriptan (Imitrex); and tranquilizers. Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have or have ever had, or anyone in your family has or has ever had, depression, bipolar disorder (mood that changes from depressed to abnormally excited), or mania (frenzied, abnormally excited mood), or have thought about or attempted suicide. Also tell your doctor if you have recently had a heart attack and if you have or have ever had seizuresor liver or heart disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking sertraline, call your doctor. you should know that sertraline may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you. ask your doctor about the safe use of alcoholic beverages while you are taking sertraline. you should know that your mental health may change in unexpected ways, especially at the beginning of your treatment and at any time your dose is increased or decreased. These changes may occur at any time if you have depression or other mental illness, whether or not you are taking sertraline or any other medication. You, your family, or your caregiver should call your doctor right away if you experience any of the following symptoms: new or worsening depression; thinking about harming or killing yourself or planning or trying to do so; extreme worry; agitation; panic attacks; difficulty falling or staying asleep; irritability; aggressive behavior; acting without thinking; severe restlessness; and frenzied abnormal excitement. Be sure that your family or caregiver knows which symptoms may be serious so they can call the doctor when you are unable to seek treatment on your own.
What side effects can
this medicine cause ?
Sertraline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: upset stomach diarrhea constipation vomiting dry mouth gas or bloating loss of appetite weight changes drowsiness dizziness excessive tiredness headache pain, burning, or tingling in the hands or feet excitement nervousness shaking hands that you cannot control difficulty falling asleep or staying asleep sore throat changes in sex drive or ability excessive sweating Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them or those listed in the IMPORTANT WARNING section, call your doctor immediately: blurred vision seizure abnormal bleeding or bruising seeing things or hearing voices that do not exist (hallucinating) Sertraline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
What storage conditions
are needed for this medication ?
Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.
What other information
should i know ?
What should i do if i
forget a dose ?
Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.