Your doctor has ordered cyclosporine, a drug used to reduce the bodys natural immune system and to prevent rejection of organ transplants (heart, kidney, liver). The drug will be added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 2-6 hours, once every day. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information. Your health care provider (doctor, nurse, or pharmacist) may measure the effectiveness and side effects of your treatment using laboratory tests and physical examinations. It is important to keep all appointments with your doctor and the laboratory. The length of treatment depends on how you respond to the medication.
How should this medicine
be used ?
Before you administer cyclosporine, look at the solution closely. It should be clear and free of floating material. Gently squeeze the bag or observe the solution container to make sure there are no leaks. Do not use the solution if it is discolored, if it contains particles, or if the bag or container leaks. Use a new solution, but show the damaged one to your health care provider. It is important that you use your medication exactly as directed. Do not stop your therapy on your own for any reason. Do not change your dosing schedule without talking to your health care provider. Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.
What special precautions
i should follow ?
Before administering cyclosporine, tell your doctor and pharmacist if you are allergic to cyclosporine or any other drugs. tell your doctor and pharmacist what prescription and nonprescription medications you are taking. While taking cyclosporine, do not take the following medications unless your doctor tells you to: allopurinol (Zyloprim), azithromycin (Zithromax), bromocriptine (Parlodel), carbamazepine (Tegretol), cimetidine (Tagamet), clarithromycin (Biaxin), danazol, diclofenac (Feldene), diltiazem (Cardizem), dirithromycin (Dynabac), erythromycin, fluconazole (Diflucan), itraconazole (Sporanox), ketoconazole (Nizoral), methotrexate, methylprednisolone (Medrol), metoclopramide (Reglan), octreotide (Sandostatin), phenobarbital, phenytoin (Dilantin), prednisolone, ranitidine (Zantac), rifabutin (Mycobutin), rifampin (Rifadin), spironolactone (Aldactone), tacrolimus (Prograf), ticlopidine (Ticlid), triamterene (Dyrenium), trimethoprim/sulfamethoxazole (Bactrim, Septra), verapamil (Calan), and vitamins. tell your doctor if you have or have ever had liver or kidney disease. tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cyclosporine, call your doctor. you should know that this drug may make you more likely to get infections. Avoid people with contagious diseases such as the flu. Keep cuts and scratches clean. Use good personal hygiene, particularly for your mouth, teeth, skin, hair, and hands. Call your doctor immediately if you have signs of an infection such as fever, sore throat, chills, and frequent and painful urination.
What side effects can
this medicine cause ?
Although side effects from cyclosporine are not common, they can occur. Tell your health care provider if any of these symptoms are severe or do not go away: upset stomach vomiting diarrhea loss of appetite increased hair growth sinusitis breast enlargement If you experience any of the following symptoms or those listed in the IMPORTANT WARNING section, call your health care provider immediately: tremors overgrowth of the gums unusual bleeding or bruising chills yellowing of the skin or eyes seizures decreased urination swelling (feet, ankles, lower legs, and hands) weight gain headache
What storage conditions
are needed for this medication ?
Your health care provider probably will give you a several-day supply of cyclosporine at a time. You may be told how to prepare each dose and how to store it properly. Store your medication only as directed. Make sure you understand what you need to store your medication properly. Keep your supplies in a clean, dry place when you are not using them, and keep all medications and supplies out of reach of children. Your health care provider will tell you how to throw away used needles, syringes, tubing, and containers to avoid accidental injury.
What other information
should i know ?
Signs of infection If you are receiving cyclosporine in your vein or under your skin, you need to know the symptoms of a catheter-related infection (an infection where the needle enters your vein or skin). If you experience any of these effects near your intravenous catheter, tell your health care provider as soon as possible: tenderness warmth irritation drainage redness swelling pain
